| Skater | Pos | Team | GP | G | A | P | +/- | PiM | GW | GT | ATOI | PPG | PPP | SHG | S | S% | BkS | Hits | P/GP | FO% | HT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| David Pastrnak | RW | BUF | 82 | 37 | 50 | 87 | +27 | 44 | 12 | 3 | 19:18 | 7 | 24 | 0 | 308 | 12.0 | 4 | 81 | 1.06 | 32 | 3 |
| Anze Kopitar | C | BUF | 82 | 20 | 65 | 85 | +30 | 10 | 7 | 1 | 21:21 | 3 | 18 | 0 | 283 | 7.1 | 9 | 39 | 1.04 | 60 | 0 |
| Sidney Crosby | C | BUF | 82 | 28 | 55 | 83 | +26 | 34 | 4 | 1 | 20:07 | 6 | 20 | 0 | 320 | 8.8 | 11 | 117 | 1.01 | 60 | 0 |
| Chris Kreider | LW | BUF | 82 | 40 | 40 | 80 | +26 | 26 | 7 | 2 | 19:09 | 13 | 23 | 0 | 337 | 11.9 | 5 | 92 | 0.98 | 44 | 2 |
| Trevor Moore | LW | BUF | 82 | 34 | 28 | 62 | +30 | 30 | 4 | 1 | 20:49 | 8 | 15 | 0 | 278 | 12.2 | 11 | 145 | 0.76 | 22 | 1 |
| Carter Verhaeghe | C | BUF | 82 | 29 | 33 | 62 | +29 | 18 | 5 | 1 | 18:23 | 4 | 12 | 0 | 246 | 11.8 | 3 | 100 | 0.76 | 30 | 0 |
| Tage Thompson | C | BUF | 82 | 21 | 27 | 48 | +9 | 35 | 3 | 3 | 13:02 | 2 | 5 | 0 | 212 | 9.9 | 7 | 114 | 0.59 | 52 | 0 |
| Nick Leddy | D | BUF | 82 | 8 | 36 | 44 | +19 | 18 | 2 | 1 | 24:06 | 7 | 16 | 0 | 125 | 6.4 | 128 | 66 | 0.54 | - | 0 |
| Justin Faulk | D | VGK / BUF | 82 | 6 | 35 | 41 | -8 | 77 | 0 | 1 | 22:10 | 3 | 11 | 0 | 93 | 6.5 | 88 | 135 | 0.50 | - | 0 |
| Connor Murphy | D | BUF | 82 | 9 | 27 | 36 | +19 | 53 | 1 | 1 | 19:44 | 2 | 6 | 0 | 85 | 10.6 | 105 | 206 | 0.44 | - | 0 |
| Daniel Sprong | LW | BUF | 82 | 12 | 20 | 32 | +9 | 10 | 1 | 1 | 13:31 | 0 | 3 | 0 | 128 | 9.4 | 7 | 35 | 0.39 | 39 | 0 |
| Chad Ruhwedel | D | BUF | 80 | 5 | 20 | 25 | +23 | 60 | 0 | 0 | 16:30 | 0 | 0 | 0 | 57 | 8.8 | 77 | 115 | 0.31 | - | 0 |
| Jack Johnson | D | BUF | 79 | 5 | 19 | 24 | +25 | 34 | 1 | 2 | 17:28 | 0 | 0 | 0 | 45 | 11.1 | 82 | 125 | 0.30 | - | 0 |
| Tyler Johnson | C | BUF | 72 | 13 | 9 | 22 | +9 | 4 | 4 | 0 | 11:57 | 0 | 0 | 0 | 109 | 11.9 | 7 | 47 | 0.31 | 45 | 0 |
| Ryan Suter | D | BUF / VGK / VAN | 81 | 4 | 17 | 21 | +23 | 41 | 1 | 0 | 20:15 | 1 | 3 | 0 | 66 | 6.1 | 88 | 135 | 0.26 | - | 0 |
| Brendan Smith | LW | BUF | 50 | 1 | 12 | 13 | +15 | 56 | 0 | 0 | 18:12 | 0 | 2 | 0 | 47 | 2.1 | 57 | 80 | 0.26 | - | 0 |
| Noah Juulsen | D | BUF | 38 | 2 | 5 | 7 | +10 | 26 | 0 | 0 | 19:00 | 0 | 2 | 0 | 32 | 6.2 | 40 | 67 | 0.18 | - | 0 |
| Nicolas Aube-Kubel | RW | BUF | 80 | 2 | 5 | 7 | -4 | 7 | 0 | 1 | 5:46 | 0 | 0 | 0 | 45 | 4.4 | 4 | 31 | 0.09 | 19 | 0 |
| Trevor Lewis | C | BUF | 82 | 4 | 1 | 5 | -4 | 2 | 0 | 0 | 7:02 | 0 | 0 | 0 | 33 | 12.1 | 7 | 9 | 0.06 | 44 | 0 |
| Sam Carrick | C | BUF | 82 | 3 | 2 | 5 | -4 | 34 | 1 | 1 | 6:57 | 0 | 0 | 0 | 46 | 6.5 | 2 | 66 | 0.06 | 54 | 0 |
| Jakub Vrana | LW | BUF | 10 | 3 | 1 | 4 | 0 | 0 | 0 | 0 | 12:02 | 0 | 0 | 0 | 17 | 17.6 | 2 | 9 | 0.40 | 0 | 0 |
| Max Crozier | D | BUF | 2 | 0 | 0 | 0 | -1 | 2 | 0 | 0 | 15:25 | 0 | 0 | 0 | 1 | 0.0 | 2 | 3 | 0.00 | - | 0 |
| 22 Skaters | 1558 | 286 | 507 | 793 | - | 621 | 53 | 20 | - | 56 | 160 | 0 | 2913 | - | 746 | 1817 | 10.3 | - | 6 |