| Skater | Pos | Team | GP | G | A | P | +/- | PiM | GW | GT | ATOI | PPG | PPP | SHG | S | S% | BkS | Hits | P/GP | FO% | HT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chris Kreider | LW | BUF | 75 | 39 | 37 | 76 | +27 | 93 | 6 | 2 | 20:23 | 7 | 13 | 0 | 351 | 11.1 | 15 | 225 | 1.01 | 37 | 2 |
| Anze Kopitar | C | BUF | 81 | 24 | 49 | 73 | +8 | 10 | 3 | 1 | 22:45 | 3 | 18 | 0 | 287 | 8.4 | 32 | 56 | 0.90 | 59 | 0 |
| Teuvo Teravainen | LW | BUF / VAN | 78 | 23 | 48 | 71 | +13 | 8 | 5 | 1 | 19:34 | 4 | 22 | 0 | 274 | 8.4 | 8 | 44 | 0.91 | 38 | 0 |
| Sidney Crosby | C | BUF | 75 | 29 | 41 | 70 | +15 | 16 | 4 | 1 | 20:00 | 7 | 17 | 0 | 280 | 10.4 | 5 | 77 | 0.93 | 57 | 0 |
| David Pastrnak | RW | BUF | 82 | 27 | 35 | 62 | +20 | 18 | 6 | 4 | 20:08 | 5 | 9 | 0 | 308 | 8.8 | 4 | 57 | 0.76 | 28 | 0 |
| Mark Giordano | D | OTT / FLA / VGK / BUF | 77 | 9 | 53 | 62 | +3 | 45 | 1 | 0 | 22:03 | 4 | 14 | 0 | 169 | 5.3 | 130 | 81 | 0.81 | - | 0 |
| Rasmus Ristolainen | D | BUF | 82 | 12 | 47 | 59 | +17 | 117 | 1 | 1 | 24:13 | 4 | 10 | 0 | 136 | 8.8 | 119 | 226 | 0.72 | - | 0 |
| Carter Verhaeghe | C | BUF | 82 | 19 | 24 | 43 | +2 | 34 | 2 | 1 | 17:39 | 5 | 10 | 1 | 231 | 8.2 | 8 | 132 | 0.52 | 42 | 1 |
| Ryan Suter | D | BUF | 79 | 7 | 35 | 42 | +3 | 12 | 2 | 0 | 24:11 | 1 | 12 | 0 | 118 | 5.9 | 110 | 24 | 0.53 | - | 0 |
| Derek Grant | C | BUF | 82 | 13 | 20 | 33 | +4 | 20 | 1 | 0 | 11:10 | 0 | 0 | 0 | 166 | 7.8 | 9 | 59 | 0.40 | 56 | 0 |
| Anders Lee | LW | BUF | 73 | 18 | 14 | 32 | +7 | 30 | 1 | 0 | 13:33 | 4 | 6 | 0 | 204 | 8.8 | 3 | 83 | 0.44 | 52 | 0 |
| Mark Borowiecki | D | BUF | 79 | 7 | 25 | 32 | +7 | 59 | 1 | 1 | 16:35 | 1 | 6 | 0 | 77 | 9.1 | 119 | 184 | 0.41 | - | 0 |
| Michael Del Zotto | D | BUF | 82 | 7 | 18 | 25 | +19 | 19 | 2 | 1 | 19:40 | 3 | 8 | 0 | 63 | 11.1 | 84 | 110 | 0.30 | - | 0 |
| Zemgus Girgensons | C | BUF | 80 | 10 | 13 | 23 | +6 | 27 | 2 | 2 | 13:57 | 0 | 0 | 0 | 158 | 6.3 | 13 | 55 | 0.29 | 34 | 0 |
| Zach Aston-Reese | LW | BUF | 82 | 11 | 11 | 22 | +8 | 28 | 4 | 0 | 10:27 | 0 | 1 | 0 | 116 | 9.5 | 13 | 97 | 0.27 | 30 | 0 |
| Jack Johnson | D | BUF | 78 | 4 | 14 | 18 | +18 | 50 | 2 | 1 | 19:48 | 2 | 3 | 0 | 72 | 5.6 | 93 | 137 | 0.23 | - | 0 |
| Trevor Moore | C | BUF | 71 | 5 | 8 | 13 | +7 | 8 | 1 | 0 | 6:33 | 0 | 0 | 0 | 50 | 10.0 | 6 | 24 | 0.18 | 30 | 0 |
| Cody Eakin | C | BUF | 77 | 4 | 7 | 11 | +1 | 2 | 1 | 1 | 5:05 | 0 | 0 | 0 | 51 | 7.8 | 5 | 10 | 0.14 | 54 | 0 |
| Ilya Lyubushkin | D | BUF | 25 | 1 | 7 | 8 | +7 | 19 | 0 | 0 | 16:24 | 1 | 2 | 0 | 20 | 5.0 | 25 | 14 | 0.32 | - | 0 |
| Tage Thompson | LW | BUF | 53 | 2 | 4 | 6 | -1 | 0 | 0 | 0 | 8:31 | 0 | 0 | 0 | 37 | 5.4 | 2 | 19 | 0.11 | 42 | 0 |
| Robert Hagg | D | BUF | 48 | 2 | 3 | 5 | +3 | 23 | 0 | 0 | 15:00 | 0 | 0 | 0 | 17 | 11.8 | 25 | 28 | 0.10 | - | 0 |
| Cole Schneider | LW | BUF | 8 | 0 | 2 | 2 | +1 | 4 | 0 | 0 | 7:33 | 0 | 0 | 0 | 2 | 0.0 | 1 | 7 | 0.25 | 25 | 0 |
| Chris Terry | LW | BUF | 14 | 0 | 1 | 1 | -1 | 22 | 0 | 0 | 12:03 | 0 | 0 | 0 | 14 | 0.0 | 4 | 18 | 0.07 | 50 | 0 |
| 23 Skaters | 1563 | 273 | 516 | 789 | - | 664 | 45 | 17 | - | 51 | 151 | 1 | 3201 | - | 833 | 1767 | 10.6 | - | 3 |