| Skater | Pos | Team | GP | G | A | P | +/- | PiM | GW | GT | ATOI | PPG | PPP | SHG | S | S% | BkS | Hits | P/GP | FO% | HT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Teuvo Teravainen | LW | BUF | 82 | 27 | 45 | 72 | +12 | 0 | 7 | 2 | 19:34 | 5 | 21 | 0 | 243 | 11.1 | 10 | 24 | 0.88 | 42 | 0 |
| Chris Kreider | LW | BUF | 77 | 31 | 35 | 66 | +31 | 43 | 8 | 1 | 17:40 | 1 | 12 | 0 | 312 | 9.9 | 4 | 196 | 0.86 | 36 | 0 |
| Sidney Crosby | C | BUF | 72 | 24 | 41 | 65 | +8 | 14 | 3 | 1 | 20:38 | 5 | 18 | 0 | 280 | 8.6 | 5 | 60 | 0.90 | 59 | 0 |
| Ryan Suter | D | BUF | 82 | 9 | 55 | 64 | +14 | 28 | 0 | 0 | 25:08 | 6 | 13 | 0 | 112 | 8.0 | 99 | 89 | 0.78 | - | 0 |
| Anze Kopitar | C | BUF | 70 | 17 | 42 | 59 | +31 | 6 | 7 | 2 | 18:04 | 3 | 14 | 0 | 230 | 7.4 | 7 | 30 | 0.84 | 58 | 0 |
| David Pastrnak | RW | OTT / BUF | 76 | 26 | 31 | 57 | +1 | 25 | 4 | 0 | 19:52 | 9 | 19 | 0 | 326 | 8.0 | 4 | 105 | 0.75 | 28 | 0 |
| Pavel Buchnevich | LW | BUF / OTT | 71 | 23 | 26 | 49 | +18 | 35 | 5 | 3 | 17:18 | 5 | 12 | 0 | 136 | 16.9 | 5 | 134 | 0.69 | 24 | 1 |
| J.T. Compher | C | BUF / OTT | 68 | 23 | 24 | 47 | +12 | 12 | 4 | 1 | 16:12 | 1 | 7 | 0 | 213 | 10.8 | 17 | 33 | 0.69 | 50 | 0 |
| Anders Lee | LW | BUF | 82 | 17 | 23 | 40 | +23 | 77 | 3 | 3 | 17:02 | 5 | 14 | 0 | 194 | 8.8 | 11 | 143 | 0.49 | 40 | 0 |
| Rasmus Ristolainen | D | BUF | 82 | 7 | 28 | 35 | +11 | 138 | 1 | 0 | 22:04 | 2 | 3 | 0 | 90 | 7.8 | 113 | 231 | 0.43 | - | 0 |
| Derek Grant | C | BUF | 82 | 17 | 10 | 27 | +1 | 25 | 1 | 1 | 12:55 | 2 | 2 | 0 | 112 | 15.2 | 20 | 70 | 0.33 | 52 | 0 |
| Travis Zajac | C | MTL / BUF / ANH | 61 | 9 | 17 | 26 | -2 | 8 | 0 | 1 | 13:32 | 0 | 1 | 0 | 98 | 9.2 | 14 | 27 | 0.43 | 57 | 0 |
| Ron Hainsey | D | BUF | 82 | 5 | 21 | 26 | +29 | 16 | 1 | 1 | 19:13 | 0 | 0 | 0 | 63 | 7.9 | 109 | 63 | 0.32 | - | 0 |
| Valeri Nichushkin | LW | VAN / BUF | 81 | 9 | 16 | 25 | -9 | 23 | 3 | 0 | 12:12 | 2 | 4 | 1 | 179 | 5.0 | 5 | 77 | 0.31 | 29 | 0 |
| Jay Bouwmeester | D | BUF | 79 | 8 | 17 | 25 | +8 | 26 | 1 | 1 | 20:24 | 2 | 6 | 1 | 92 | 8.7 | 103 | 74 | 0.32 | - | 0 |
| Michael Del Zotto | D | BUF | 78 | 4 | 18 | 22 | -2 | 50 | 0 | 0 | 17:31 | 1 | 4 | 0 | 58 | 6.9 | 71 | 105 | 0.28 | - | 0 |
| Colin Wilson | C | BUF | 82 | 9 | 12 | 21 | +6 | 6 | 2 | 1 | 9:42 | 0 | 1 | 0 | 75 | 12.0 | 3 | 38 | 0.26 | 31 | 0 |
| Nikita Gusev (R) | LW | BUF / VAN | 77 | 9 | 11 | 20 | -4 | 0 | 1 | 1 | 13:40 | 2 | 5 | 0 | 160 | 5.6 | 7 | 14 | 0.26 | 27 | 0 |
| Zemgus Girgensons | C | ANH / BUF | 78 | 7 | 12 | 19 | -3 | 4 | 0 | 2 | 13:38 | 0 | 0 | 0 | 153 | 4.6 | 18 | 73 | 0.24 | 36 | 0 |
| Dakota Mermis | D | BUF | 82 | 7 | 12 | 19 | +6 | 48 | 2 | 0 | 16:59 | 5 | 7 | 0 | 82 | 8.5 | 80 | 105 | 0.23 | - | 0 |
| Zach Aston-Reese | LW | BUF | 82 | 7 | 11 | 18 | +1 | 28 | 0 | 1 | 10:36 | 1 | 2 | 0 | 92 | 7.6 | 12 | 126 | 0.22 | 27 | 0 |
| Loui Eriksson | LW | STL / VGK / BUF | 83 | 8 | 6 | 14 | -9 | 0 | 1 | 0 | 10:57 | 0 | 0 | 1 | 74 | 10.8 | 17 | 5 | 0.17 | 37 | 0 |
| Christian Djoos | D | TBL / PHL / BUF | 50 | 2 | 12 | 14 | +21 | 2 | 1 | 0 | 16:55 | 2 | 5 | 0 | 38 | 5.3 | 44 | 13 | 0.28 | - | 0 |
| Kyle Rau | C | TOR / BUF / MTL | 55 | 7 | 5 | 12 | -12 | 12 | 0 | 0 | 11:49 | 0 | 0 | 1 | 49 | 14.3 | 6 | 23 | 0.22 | 50 | 0 |
| Justin Bailey | LW | BUF / ARI | 78 | 4 | 7 | 11 | +6 | 22 | 1 | 0 | 7:06 | 0 | 0 | 0 | 58 | 6.9 | 4 | 45 | 0.14 | 26 | 0 |
| Kurtis MacDermid | D | BUF / OTT | 29 | 4 | 3 | 7 | +2 | 58 | 0 | 0 | 17:06 | 0 | 0 | 0 | 15 | 26.7 | 26 | 83 | 0.24 | - | 0 |
| Carter Verhaeghe | C | LAK / BUF | 36 | 1 | 3 | 4 | -13 | 6 | 0 | 0 | 13:03 | 1 | 4 | 0 | 21 | 4.8 | 3 | 19 | 0.11 | 29 | 0 |
| Byron Froese | C | DAL / BUF / PHL | 24 | 2 | 0 | 2 | -1 | 7 | 0 | 0 | 6:19 | 0 | 0 | 0 | 13 | 15.4 | 3 | 10 | 0.08 | 53 | 0 |
| Michael Amadio | C | BUF | 15 | 1 | 0 | 1 | -1 | 2 | 0 | 1 | 7:14 | 0 | 0 | 0 | 8 | 12.5 | 1 | 5 | 0.07 | 45 | 0 |
| Andy Welinski | D | FLA / BUF | 17 | 0 | 1 | 1 | 0 | 8 | 0 | 0 | 15:31 | 0 | 0 | 0 | 8 | 0.0 | 15 | 26 | 0.06 | - | 0 |
| Taylor Fedun | D | BUF | 1 | 0 | 0 | 0 | +1 | 2 | 0 | 0 | 12:01 | 0 | 0 | 0 | 0 | - | 0 | 2 | 0.00 | - | 0 |
| Chris Terry | LW | BUF | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12:05 | 0 | 0 | 0 | 0 | - | 0 | 2 | 0.00 | 37 | 0 |
| 32 Skaters | 2016 | 324 | 544 | 868 | - | 731 | 56 | 23 | - | 60 | 174 | 4 | 3584 | - | 836 | 2050 | 11.88 | - | 1 |