| Skater | Pos | Team | GP | G | A | P | +/- | PiM | GW | GT | ATOI | PPG | PPP | SHG | S | S% | BkS | Hits | P/GP | FO% | HT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sidney Crosby | C | BUF | 82 | 40 | 60 | 100 | +46 | 40 | 9 | 1 | 20:07 | 8 | 25 | 1 | 338 | 11.8 | 7 | 70 | 1.22 | 58 | 1 |
| Jussi Jokinen | LW | BUF | 82 | 31 | 53 | 84 | +46 | 6 | 5 | 4 | 20:58 | 13 | 24 | 0 | 251 | 12.4 | 12 | 34 | 1.02 | 45 | 0 |
| Shane Doan | RW | BUF | 82 | 34 | 38 | 72 | +40 | 90 | 6 | 2 | 20:39 | 5 | 16 | 0 | 240 | 14.2 | 6 | 246 | 0.88 | 45 | 0 |
| Rasmus Ristolainen | D | BUF | 76 | 17 | 55 | 72 | +33 | 113 | 5 | 3 | 25:24 | 9 | 20 | 0 | 167 | 10.2 | 93 | 149 | 0.95 | - | 0 |
| Kevin Shattenkirk | D | BUF | 78 | 12 | 51 | 63 | +37 | 54 | 1 | 0 | 24:12 | 8 | 26 | 0 | 126 | 9.5 | 79 | 120 | 0.81 | - | 0 |
| Anze Kopitar | C | CGY / BUF | 74 | 28 | 33 | 61 | +8 | 28 | 3 | 2 | 18:10 | 8 | 20 | 1 | 223 | 12.6 | 12 | 64 | 0.82 | 60 | 0 |
| Tomas Plekanec | C | BUF / CGY / NYR | 75 | 14 | 47 | 61 | +21 | 20 | 4 | 0 | 19:05 | 3 | 25 | 0 | 207 | 6.8 | 17 | 79 | 0.81 | 55 | 0 |
| Michael Del Zotto | D | DET / NYR / BUF | 79 | 13 | 36 | 49 | +7 | 131 | 2 | 2 | 21:16 | 6 | 18 | 0 | 142 | 9.2 | 114 | 206 | 0.62 | - | 0 |
| Zack Smith | C | VAN / BUF | 85 | 23 | 22 | 45 | -2 | 124 | 2 | 2 | 17:12 | 3 | 11 | 1 | 181 | 12.7 | 16 | 172 | 0.53 | 54 | 0 |
| Brent Seabrook | D | OTT / BUF | 63 | 8 | 34 | 42 | -1 | 82 | 0 | 2 | 22:44 | 7 | 23 | 0 | 119 | 6.7 | 71 | 108 | 0.67 | - | 0 |
| Tyler Myers | D | BUF | 82 | 8 | 34 | 42 | +13 | 87 | 0 | 0 | 20:47 | 1 | 11 | 0 | 106 | 7.5 | 80 | 115 | 0.51 | - | 0 |
| Chris Kreider | LW | TOR / CHI / BUF | 85 | 12 | 24 | 36 | -16 | 93 | 0 | 0 | 17:02 | 3 | 9 | 0 | 213 | 5.6 | 6 | 131 | 0.42 | 39 | 0 |
| Riley Sheahan | C | BUF / ANH / NJD | 83 | 15 | 18 | 33 | +6 | 34 | 1 | 1 | 14:33 | 6 | 9 | 0 | 147 | 10.2 | 8 | 52 | 0.40 | 59 | 0 |
| Dylan Larkin (R) | C | BUF / CGY | 78 | 17 | 13 | 30 | 0 | 26 | 1 | 2 | 14:36 | 0 | 5 | 1 | 101 | 16.8 | 5 | 58 | 0.38 | 36 | 0 |
| Ryan Murray | D | BUF | 64 | 6 | 23 | 29 | +3 | 38 | 1 | 0 | 19:04 | 6 | 11 | 0 | 69 | 8.7 | 53 | 56 | 0.45 | 50 | 0 |
| Rickard Rakell | C | BUF | 82 | 14 | 14 | 28 | 0 | 37 | 4 | 1 | 15:55 | 9 | 17 | 0 | 130 | 10.8 | 9 | 120 | 0.34 | 49 | 0 |
| Thomas Vanek | LW | BUF | 82 | 12 | 12 | 24 | +17 | 6 | 1 | 3 | 12:27 | 3 | 8 | 0 | 102 | 11.8 | 4 | 16 | 0.29 | 40 | 0 |
| Antoine Vermette | C | BUF | 73 | 9 | 14 | 23 | -4 | 27 | 4 | 0 | 14:17 | 1 | 7 | 1 | 157 | 5.7 | 15 | 77 | 0.32 | 59 | 0 |
| Teuvo Teravainen (R) | C | BUF | 82 | 11 | 8 | 19 | +2 | 12 | 2 | 1 | 10:43 | 0 | 0 | 0 | 149 | 7.4 | 6 | 19 | 0.23 | 44 | 0 |
| Anders Lee | LW | BUF | 75 | 9 | 10 | 19 | -5 | 63 | 2 | 2 | 7:59 | 0 | 1 | 0 | 80 | 11.2 | 1 | 61 | 0.25 | 31 | 0 |
| Kevan Miller | D | BUF / NYR | 79 | 8 | 10 | 18 | +11 | 109 | 1 | 1 | 16:55 | 1 | 2 | 0 | 48 | 16.7 | 85 | 135 | 0.23 | - | 0 |
| David Perron | LW | OTT / CAR / NYI / BUF | 71 | 7 | 8 | 15 | +3 | 55 | 0 | 1 | 11:57 | 0 | 1 | 0 | 93 | 7.5 | 5 | 111 | 0.21 | 22 | 0 |
| Luke Glendening | C | BUF | 72 | 4 | 10 | 14 | +1 | 28 | 3 | 0 | 10:32 | 0 | 0 | 1 | 48 | 8.3 | 20 | 67 | 0.19 | 55 | 0 |
| Brayden McNabb | D | BUF / VAN / BOS | 73 | 4 | 10 | 14 | 0 | 110 | 0 | 0 | 14:48 | 1 | 4 | 0 | 41 | 9.8 | 45 | 153 | 0.19 | - | 0 |
| Jacob Josefson | C | BUF / NYR | 55 | 8 | 5 | 13 | 0 | 16 | 2 | 1 | 10:10 | 0 | 0 | 0 | 59 | 13.6 | 8 | 25 | 0.24 | 46 | 0 |
| Jordan Oesterle | D | BUF | 28 | 1 | 6 | 7 | +1 | 10 | 1 | 0 | 13:04 | 0 | 1 | 0 | 12 | 8.3 | 22 | 13 | 0.25 | - | 0 |
| Zemgus Girgensons | C | ANH / BUF | 34 | 1 | 4 | 5 | 0 | 6 | 0 | 0 | 7:41 | 0 | 0 | 0 | 26 | 3.8 | 2 | 19 | 0.15 | 46 | 0 |
| Dylan McIlrath (R) | D | BUF | 21 | 0 | 2 | 2 | +4 | 49 | 0 | 0 | 12:34 | 0 | 0 | 0 | 9 | 0.0 | 15 | 45 | 0.10 | - | 0 |
| Oscar Lindberg (R) | C | BUF | 6 | 1 | 0 | 1 | 0 | 2 | 0 | 0 | 5:19 | 0 | 0 | 0 | 3 | 33.3 | 0 | 2 | 0.17 | 43 | 0 |
| Mark Pysyk | D | BUF | 10 | 0 | 1 | 1 | -4 | 2 | 0 | 0 | 13:48 | 0 | 0 | 0 | 3 | 0.0 | 7 | 5 | 0.10 | - | 0 |
| Conor Sheary (R) | LW | BUF | 8 | 0 | 0 | 0 | +2 | 4 | 0 | 0 | 5:00 | 0 | 0 | 0 | 2 | 0.0 | 0 | 0 | 0.00 | 29 | 0 |
| 31 Skaters | 2019 | 367 | 655 | 1022 | - | 1502 | 60 | 31 | - | 101 | 294 | 6 | 3592 | - | 823 | 2528 | 13.75 | - | 1 |