| Skater | Pos | Team | GP | G | A | P | +/- | PiM | GW | GT | ATOI | PPG | SHG | S | S% | BkS | Hits | P/GP | FO% | HT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Daniel Briere | RW | BUF / NYR | 81 | 47 | 55 | 102 | +35 | 39 | 7 | 0 | 17:55 | 16 | 0 | 329 | 14.3 | 7 | 60 | 1.26 | 55 | 0 |
| Jason Pominville | RW | BUF | 82 | 33 | 62 | 95 | +43 | 22 | 6 | 0 | 18:17 | 13 | 0 | 297 | 11.1 | 11 | 66 | 1.16 | 54 | 1 |
| Sidney Crosby | C | BUF | 82 | 31 | 63 | 94 | +18 | 106 | 7 | 0 | 18:33 | 13 | 1 | 280 | 11.1 | 6 | 128 | 1.15 | 53 | 0 |
| Derek Roy | C | BUF | 82 | 37 | 51 | 88 | +42 | 41 | 6 | 1 | 20:29 | 8 | 1 | 268 | 13.8 | 16 | 47 | 1.07 | 55 | 1 |
| Marian Gaborik | RW | BUF | 81 | 34 | 46 | 80 | +18 | 101 | 6 | 0 | 16:32 | 11 | 0 | 302 | 11.3 | 4 | 80 | 0.99 | 32 | 1 |
| Chris Pronger | D | BUF | 82 | 24 | 51 | 75 | +10 | 146 | 4 | 0 | 23:50 | 14 | 0 | 146 | 16.4 | 96 | 138 | 0.91 | - | 1 |
| Thomas Vanek | LW | BUF | 82 | 32 | 35 | 67 | +33 | 46 | 4 | 0 | 15:18 | 12 | 0 | 246 | 13.0 | 6 | 90 | 0.82 | 42 | 0 |
| Marco Sturm | LW | MTL / PIT / BUF | 79 | 22 | 40 | 62 | +15 | 18 | 4 | 1 | 14:50 | 8 | 0 | 186 | 11.8 | 7 | 54 | 0.78 | 31 | 1 |
| Colby Armstrong | RW | NYR / BUF | 83 | 20 | 29 | 49 | +12 | 30 | 0 | 0 | 17:53 | 2 | 0 | 196 | 10.2 | 11 | 58 | 0.59 | 28 | 0 |
| Antti Miettinen | LW | NYR / BUF | 83 | 18 | 30 | 48 | +14 | 42 | 4 | 0 | 14:56 | 4 | 0 | 159 | 11.3 | 6 | 49 | 0.58 | 53 | 0 |
| Teppo Numminen | D | BUF | 82 | 8 | 36 | 44 | +35 | 31 | 0 | 0 | 20:34 | 4 | 1 | 100 | 8.0 | 68 | 22 | 0.54 | - | 0 |
| Jochen Hecht | C | BUF | 82 | 19 | 22 | 41 | +8 | 16 | 3 | 0 | 17:40 | 0 | 0 | 163 | 11.7 | 17 | 27 | 0.50 | 49 | 0 |
| Jaroslav Spacek | D | DET / VAN / OTT / BUF | 80 | 8 | 32 | 40 | +7 | 139 | 0 | 0 | 21:52 | 7 | 0 | 114 | 7.0 | 96 | 161 | 0.50 | - | 0 |
| Marc-Andre Bergeron | D | BUF / TOR / OTT | 81 | 10 | 29 | 39 | -25 | 16 | 0 | 0 | 19:20 | 5 | 0 | 103 | 9.7 | 57 | 24 | 0.48 | 20 | 0 |
| Henrik Tallinder | D | BUF | 82 | 7 | 30 | 37 | +33 | 29 | 1 | 0 | 17:38 | 3 | 0 | 67 | 10.4 | 75 | 16 | 0.45 | - | 0 |
| Hal Gill | D | BUF | 82 | 6 | 24 | 30 | +30 | 224 | 1 | 0 | 18:05 | 2 | 0 | 60 | 10.0 | 99 | 202 | 0.37 | - | 0 |
| Daniel Paille | LW | BUF | 82 | 14 | 15 | 29 | +11 | 8 | 2 | 0 | 12:28 | 2 | 0 | 152 | 9.2 | 8 | 25 | 0.35 | 42 | 1 |
| Anton Volchenkov | D | BUF | 82 | 6 | 20 | 26 | +19 | 196 | 0 | 0 | 21:07 | 4 | 0 | 83 | 7.2 | 93 | 218 | 0.32 | - | 0 |
| Paul Gaustad | C | BUF | 82 | 5 | 18 | 23 | +1 | 104 | 0 | 0 | 12:15 | 1 | 0 | 83 | 6.0 | 9 | 152 | 0.28 | 57 | 0 |
| Drew Stafford | RW | BUF | 82 | 11 | 7 | 18 | +9 | 34 | 3 | 0 | 9:01 | 1 | 0 | 79 | 13.9 | 2 | 65 | 0.22 | 44 | 0 |
| Mike Mottau | D | BUF | 63 | 1 | 9 | 10 | +25 | 23 | 1 | 0 | 13:09 | 0 | 0 | 13 | 7.7 | 25 | 23 | 0.16 | - | 0 |
| Adam Mair | C | BUF | 68 | 1 | 7 | 8 | -1 | 60 | 0 | 1 | 8:19 | 1 | 0 | 40 | 2.5 | 11 | 59 | 0.12 | 53 | 0 |
| Clarke MacArthur (R) | LW | BUF | 42 | 1 | 6 | 7 | -3 | 12 | 0 | 0 | 6:36 | 0 | 0 | 30 | 3.3 | 0 | 5 | 0.17 | 50 | 0 |
| Patrick Kaleta (R) | RW | BUF | 18 | 0 | 1 | 1 | 0 | 14 | 0 | 0 | 7:57 | 0 | 0 | 5 | 0.0 | 4 | 18 | 0.06 | 25 | 0 |
| Cody McLeod (R) | LW | BUF | 7 | 0 | 0 | 0 | -3 | 24 | 0 | 0 | 7:09 | 0 | 0 | 0 | - | 0 | 9 | 0.00 | 0 | 0 |
| 25 Skaters | 1832 | 395 | 718 | 1113 | - | 1521 | 59 | 3 | - | 131 | 3 | 3501 | - | 734 | 1796 | 13.83 | - | 6 |